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Current Biology
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Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2
Posted: September 2nd, 2010, 10:00pm MDT
Lisa Martine Lister, Anna Kouznetsova, Louise Ann Hyslop, Dimitrios Kalleas, Sarah Louise Pace, Jaclyn Catharina Barel, Abinaya Nathan, Vasileios Floros, Caroline Adelfalk, Yoshinori Watanabe, Rolf Jessberger, Thomas B. Kirkwood, Christer Höög, Mary Herbert. BackgroundThe growing trend for women to postpone childbearing has resulted in a dramatic increase in the incidence of trisomic pregnancies. Maternal age-related miscarriage and birth defects are ....
