PubAlert » Current Biology » Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

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Current Biology

• September 02, 2010
• 

  Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

  Posted: September 2nd, 2010, 10:00pm MDT

  Teresa Chiang, Francesca E. Duncan, Karen Schindler, Richard M. Schultz, Michael A. Lampson. Aneuploidy arising early in development is the leading genetic cause of birth defects and developmental disabilities in humans. Most errors in chromosome number originate from the egg, and materna....